Alkoxyamine-mediated radical synthesis of indolinones and indolines

Corinne Leroi; Denis Bertin; Pierre-Emmanuel Dufils; Didier Gigmes; Sylvain Marque; Paul Tordo; Jean-Luc Couturier; Olivier Guerret; Marco A Ciufolini

doi:10.1021/ol0358049

Alkoxyamine-mediated radical synthesis of indolinones and indolines

Org Lett. 2003 Dec 25;5(26):4943-5. doi: 10.1021/ol0358049.

Authors

Corinne Leroi¹, Denis Bertin, Pierre-Emmanuel Dufils, Didier Gigmes, Sylvain Marque, Paul Tordo, Jean-Luc Couturier, Olivier Guerret, Marco A Ciufolini

Affiliation

¹ Université Claude Bernard Lyon 1 and Ecole Supérieure de Chimie, Physique, Electronique de Lyon, CNRS UMR 5622, 43 Boulevard du 11 Novembre 1918, 69622 Villeurbanne, France.

PMID: 14682735
DOI: 10.1021/ol0358049

Abstract

Thermolysis of alpha-alkoxyamino propionanilides produces indolinones, whereas thermal reaction of N-allylaniline derivatives with various Tordo-type alkoxyamines results in formation of indolines in the radical regime. [reaction: see text]