[Significance of chromatographic methods coupled with mass spectrometry for identification of drugs for medico-legal purposes exemplified by chlorphenoxamine]

Arch Med Sadowej Kryminol. 2003 Apr-Jun;53(2):137-49.
[Article in Polish]

Abstract

This work presented the death of the 17-year old women M.F. The direct cause of death was violent strangulation. Toxicological investigation made possible a wider explanation of the case, since M.F. was under influence of associative action of diphenhydramine and ethanol which could not avoid having an influence on the tragic events accompanying the death. Besides a comprehensive interpretation of the toxicological results in medico--legal aspect large methodic documentation has been presented which proves the usefulness of chromatographic methods coupled with spectrometry for identification of xenobiotics found.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adolescent
  • Autopsy / methods
  • Caffeine / analysis
  • Caffeine / blood
  • Diphenhydramine / analysis
  • Diphenhydramine / blood
  • Ethanol / analysis
  • Ethanol / blood
  • Ethylamines / analysis*
  • Ethylamines / blood
  • Female
  • Forensic Medicine / methods
  • Gas Chromatography-Mass Spectrometry* / methods
  • Homicide*
  • Humans
  • Hypnotics and Sedatives / analysis
  • Kidney / chemistry
  • Liver / chemistry
  • Retina / chemistry
  • Substance Abuse Detection / instrumentation
  • Substance Abuse Detection / methods*
  • Time Factors

Substances

  • Ethylamines
  • Hypnotics and Sedatives
  • Caffeine
  • Ethanol
  • chlorphenoxamine
  • Diphenhydramine