[Study on the blood glucose and lipid of soybean milk rich in chromium to diabetic rats]

Wei Sheng Yan Jiu. 2003 Sep;32(5):484-7.
[Article in Chinese]

Abstract

To reveal the effects of soybean milk with chromium fortification on the blood glucose and lipid of diabetic rat dealt with alloxan. The alloxan diabetic rats were divided into three groups and were fed continuously with the soybean milk without chromium fortification [Cr 0.25 microgram/(d.kg BW)], and with low chromium [Cr 30 micrograms/(d.kg BW)] and high chromium fortification [Cr 300 micrograms/(d.kg BW)] respectively for four weeks. The blood samples from all experimental rats tail vine were obtained each week. Blood glucose, total cholesterol, triglyceride, very low-density lipoprotein, high-density lipoprotein and insulin were tested.

Results: The concentrations of blood glucose, total cholesterol, triglyceride, very low-density lipoprotein and insulin were lowered significantly, and high-density lipoprotein was elevated significantly in the rats fed by soybean milk with high chromium fortification during the experimental period. The effect of improving blood glucose concentration in the group of soybean milk with high chromium fortification is significantly better than that in other groups.

Conclusion: The present investigation indicates that soybean milk with chromium fortification can improve glucose and lipid metabolism of diabetic rat, and has a potential use in the diabetes mellitus prevention and control.

Publication types

  • English Abstract

MeSH terms

  • Alloxan
  • Animals
  • Blood Glucose / metabolism*
  • Chromium
  • Diabetes Mellitus, Experimental / diet therapy*
  • Diabetes Mellitus, Experimental / metabolism
  • Food, Fortified
  • Insulin / blood
  • Lipids / blood*
  • Male
  • Rats
  • Rats, Wistar
  • Soy Foods*

Substances

  • Blood Glucose
  • Insulin
  • Lipids
  • Chromium
  • Alloxan