Are fetal cells in maternal plasma really there? We think they are

J Hum Genet. 2003;48(12):665-667. doi: 10.1007/s10038-003-0084-5. Epub 2003 Nov 8.

Abstract

We describe a single centrifugation procedure that resulted in the recovery of fetal cells in maternal blood in 77% of normal male pregnancies and in 87.5% of aneuploid pregnancies. There was an average yield of one fetal cell/1,993 maternal cells in normal pregnancies, which increased to one in 994, in aneuploid pregnancies.

MeSH terms

  • Centrifugation / methods
  • Female
  • Fetal Blood*
  • Fetomaternal Transfusion
  • Humans
  • In Situ Hybridization, Fluorescence
  • Karyotyping
  • Male
  • Maternal-Fetal Exchange
  • Pregnancy
  • Prenatal Diagnosis / methods*