Glycotentacles: synthesis of cyclic glycopeptides, toward a tailored blocker of influenza virus hemagglutinin

Angew Chem Int Ed Engl. 2003 Nov 3;42(42):5186-9. doi: 10.1002/anie.200351640.

Authors

Takashi Ohta¹, Nobuaki Miura, Naoki Fujitani, Fumio Nakajima, Kenichi Niikura, Reiko Sadamoto, Chao-Tan Guo, Takashi Suzuki, Yasuo Suzuki, Kenji Monde, Shin-Ichiro Nishimura

Affiliation

¹ Division of Biological Sciences, Graduate School of Science, Frontier Research Center for Post-genomic Science and Technology, Hokkaido University, Kita 21 Nishi 11, Sapporo 001-0021, Japan.

PMID: 14601167
DOI: 10.1002/anie.200351640

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antiviral Agents / chemical synthesis*
Antiviral Agents / chemistry
Antiviral Agents / pharmacology
Binding, Competitive
Drug Design*
Glycopeptides / chemical synthesis*
Glycopeptides / chemistry
Glycopeptides / pharmacology
Hemagglutination Tests
Hemagglutinin Glycoproteins, Influenza Virus / metabolism*
Ligands
Models, Molecular
Molecular Structure
Peptides, Cyclic / chemical synthesis*
Peptides, Cyclic / chemistry
Peptides, Cyclic / pharmacology
Protein Conformation

Substances

Antiviral Agents
Glycopeptides
Hemagglutinin Glycoproteins, Influenza Virus
Ligands
Peptides, Cyclic