Abstract
Two isoflavonoids, named olibergin A (1) and B (2) were isolated from the stem bark of Dalbergia oliveri (Leguminosae). Along with three previously known compounds, they are inhibitors of Epstein-Barr virus early antigen activation induced by 12-O-tetradecanoylphorbol-13-acetate in Raji cells. Their structures were elucidated on the basis of spectroscopic analyses.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Antigens, Viral / biosynthesis
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification
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Antineoplastic Agents, Phytogenic / pharmacology
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Cell Line
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Cell Survival / drug effects
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Dalbergia / chemistry*
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Humans
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Inhibitory Concentration 50
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Isoflavones / chemistry
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Isoflavones / isolation & purification*
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Isoflavones / pharmacology
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Plant Bark / chemistry
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Plant Stems / chemistry
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Tetradecanoylphorbol Acetate / pharmacology
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Virus Activation / drug effects
Substances
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Antigens, Viral
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Antineoplastic Agents, Phytogenic
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Isoflavones
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Tetradecanoylphorbol Acetate