[The use of monoclonal antibodies in studying the causative agents of viral hemorrhagic fevers]

G V Borisevich; V N Lebedev; Iu I Pashchenko; S V Ruchko; R A Khamitov; S N Ionov; V A Maksimov; V N Orlov

[The use of monoclonal antibodies in studying the causative agents of viral hemorrhagic fevers]

Vopr Virusol. 2003 Sep-Oct;48(5):4-8.

[Article in Russian]

Authors

G V Borisevich, V N Lebedev, Iu I Pashchenko, S V Ruchko, R A Khamitov, S N Ionov, V A Maksimov, V N Orlov

PMID: 14598472

Abstract

The most promising trends of using monoclonal antibodies (Mabs) in virology research of the viral hemorrhagic-fevers' agents are related with studying viral antigen structure and with developing diagnostic preparations for indicating and identifying infectious agents of the mentioned pathologies. The methodological specificity of obtaining the Mabs to viral hemorrhagic-fevers' agents as well as data on its practical use are discussed.

Publication types

English Abstract
Review

MeSH terms

Animals
Antibodies, Monoclonal / immunology*
Antibodies, Viral / immunology*
Antigens, Viral / analysis*
Arenaviridae / immunology
Arenaviridae / isolation & purification*
Bunyaviridae / immunology
Bunyaviridae / isolation & purification*
Filoviridae / immunology
Filoviridae / isolation & purification*
Flaviviridae / immunology
Flaviviridae / isolation & purification*
Hemorrhagic Fevers, Viral / diagnosis
Hemorrhagic Fevers, Viral / virology*
Humans
Research

Substances

Antibodies, Monoclonal
Antibodies, Viral
Antigens, Viral