Cytomegalovirus. A common virus causing serious disease

Aust Fam Physician. 2003 Oct;32(10):789-93.

Abstract

Background: Human cytomegalovirus (CMV) is a herpes virus that causes severe illness and death in people whose immune systems are compromised, including organ and bone marrow transplant recipients, HIV infected people, those on immunosuppressive drugs and newborns infected during pregnancy.

Objective: This article aims to present a clear guide to diagnosis and treatment of CMV in at risk patients in the community.

Discussion: Cytomegalovirus is a common infection in the community, but diagnosis is often seen as difficult. The use of careful clinical assessment tests and a clear diagnostic algorithm can provide appropriate diagnosis in most immunocompromised patients, pregnant women and newborns with CMV. Treatment strategies and available antivirals are improving, complementing the advances made with diagnostic techniques and algorithms.

Publication types

  • Review

MeSH terms

  • Adult
  • Age Distribution
  • Antiviral Agents / therapeutic use
  • Australia / epidemiology
  • Carrier State*
  • Child, Preschool
  • Cytomegalovirus / isolation & purification*
  • Cytomegalovirus Infections / diagnosis*
  • Cytomegalovirus Infections / drug therapy
  • Cytomegalovirus Infections / epidemiology*
  • Cytomegalovirus Infections / immunology
  • DNA, Viral / analysis
  • Female
  • Humans
  • Immunocompromised Host*
  • Incidence
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical
  • Male
  • Polymerase Chain Reaction / methods
  • Pregnancy
  • Prognosis
  • Risk Assessment
  • Severity of Illness Index
  • Sex Distribution

Substances

  • Antiviral Agents
  • DNA, Viral