MetaFluxNet: the management of metabolic reaction information and quantitative metabolic flux analysis

Bioinformatics. 2003 Nov 1;19(16):2144-6. doi: 10.1093/bioinformatics/btg271.

Abstract

Summary: MetaFluxNet is a program package for managing information on the metabolic reaction network and for quantitatively analyzing metabolic fluxes in an interactive and customized way. It allows users to interpret and examine metabolic behavior in response to genetic and/or environmental modifications. As a result, quantitative in silico simulations of metabolic pathways can be carried out to understand the metabolic status and to design the metabolic engineering strategies. The main features of the program include a well-developed model construction environment, user-friendly interface for metabolic flux analysis (MFA), comparative MFA of strains having different genotypes under various environmental conditions, and automated pathway layout creation.

Availability: http://mbel.kaist.ac.kr/

Supplementary information: A manual for MetaFluxNet is available as PDF file.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Database Management Systems*
  • Information Storage and Retrieval / methods*
  • Metabolism / physiology*
  • Models, Biological*
  • Proteome / physiology*
  • Proteomics / methods*
  • Software
  • Software Design
  • User-Computer Interface*

Substances

  • Proteome