Novel transporters from hemiascomycete yeasts

J Mol Microbiol Biotechnol. 2003;6(1):19-28. doi: 10.1159/000073405.

Abstract

We screened nearly one thousand random sequenced targets obtained by partial sequencing of 13 hemiascomycete genomes identified by higher amino acid sequence similarity to a non-Saccharomyces cerevisiae protein than to a S. Cerevisiae protein. Among those sequences we have identified 36 novel phylogenetic clusters of putative transporters which, according to the Transport Commission system (TC-DB, 2002; http:// tcdb.ucsd.edu/tcdb), do not belong to acknowledged S. Cerevisiae protein families [De Hertogh et al.: Funct. Integr. Genomics 2002;2:154-170; http://cbi.labri.u-bordeaux.fr/Genolevures]. These novel hemiascomycete transporters comprise 3 channels, 23 secondary transporters, 5 primary transporters and 5 membrane proteins of unknown function.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ascomycota / genetics*
  • Ascomycota / metabolism*
  • Carrier Proteins / classification
  • Carrier Proteins / genetics*
  • Carrier Proteins / metabolism*
  • Databases, Genetic
  • Fungal Proteins / classification
  • Fungal Proteins / genetics*
  • Fungal Proteins / metabolism*
  • Genome, Fungal
  • Saccharomyces cerevisiae / genetics
  • Saccharomyces cerevisiae / metabolism
  • Saccharomyces cerevisiae Proteins / genetics
  • Saccharomyces cerevisiae Proteins / metabolism

Substances

  • Carrier Proteins
  • Fungal Proteins
  • Saccharomyces cerevisiae Proteins