Influence of tamoxifen on the mandible bone and hard teeth tissues of animals

Pol J Pharmacol. 2003 Jul-Aug;55(4):625-30.

Abstract

Tamoxifen, protactedly used, can cause disadvantageous changes in the bones and in the hard teeth tissues. The aim of this paper was to define to what extent tamoxifen given to the animals influences the structure of the mandible bone and the hard teeth tissues.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Calcium / metabolism
  • Dose-Response Relationship, Drug
  • Estrogen Antagonists / pharmacology*
  • Female
  • Magnesium / metabolism
  • Mandible / drug effects*
  • Mandible / metabolism
  • Phosphorus / metabolism
  • Rats
  • Rats, Wistar
  • Tamoxifen / pharmacology*
  • Tooth / drug effects*
  • Tooth / metabolism

Substances

  • Estrogen Antagonists
  • Tamoxifen
  • Phosphorus
  • Magnesium
  • Calcium