The level of aberrant cells in various tissues of bank vole depending on doses and radionuclide balance in organism

Tsitol Genet. 2003 Jul-Aug;37(4):10-5.

Abstract

A regression analysis shows the direct linear relation between 137Cs accumulation in rodents and the level of aberrant cells. For 90Sr this trend was negative. The dose relationship was the same with 137Cs. The trends were negative 1 month later after feeding of animals with clean food. Correspondingly the dose relationship was also negative. The levels of cells with apoptosis features were different in animals from the control and the radiocontaminated sites. The analysis has revealed the correlation between the 90Sr content in animal body and the number of alveolar macrophages containing micronuclei. The relationship was revealed between the 137Cs content in the animal body and the number of intestinal epithelial cells with micronuclei.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Apoptosis / radiation effects
  • Arvicolinae / genetics*
  • Bone Marrow Cells / radiation effects
  • Cesium Radioisotopes / analysis
  • Chromosome Aberrations*
  • Dose-Response Relationship, Radiation
  • Half-Life
  • Intestinal Mucosa / radiation effects
  • Macrophages, Alveolar / radiation effects
  • Micronucleus Tests
  • Radiation Dosage
  • Radioactive Pollutants / analysis
  • Radioisotopes / analysis*
  • Republic of Belarus
  • Strontium Radioisotopes / analysis
  • Thymus Gland / radiation effects

Substances

  • Cesium Radioisotopes
  • Radioactive Pollutants
  • Radioisotopes
  • Strontium Radioisotopes