Synthesis of oligonucleotide-peptide PEG-conjugated: the EGG (oligonucleotide)-chicken (peptide) dilemma?

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1255-7. doi: 10.1081/NCN-120022849.

Abstract

The synthesis of a peptide-PEG-oligonucleotide chimera is compared when starting from the peptide or from the oligonucleotide sequence.

Publication types

  • Comparative Study

MeSH terms

  • Base Sequence
  • Indicators and Reagents
  • Nucleic Acid Hybridization
  • Peptide Nucleic Acids / chemical synthesis*
  • Polyethylene Glycols*

Substances

  • Indicators and Reagents
  • Peptide Nucleic Acids
  • Polyethylene Glycols