Epidemiological study of resistance to nalidixic acid and other antibiotics in clinical Yersinia enterocolitica O:3 isolates

S Capilla; P Goñi; M C Rubio; J Castillo; L Millán; P Cerdá; J Sahagún; C Pitart; A Beltrán; R Gómez-Lus

doi:10.1128/JCM.41.10.4876-4878.2003

Epidemiological study of resistance to nalidixic acid and other antibiotics in clinical Yersinia enterocolitica O:3 isolates

J Clin Microbiol. 2003 Oct;41(10):4876-8. doi: 10.1128/JCM.41.10.4876-4878.2003.

Authors

S Capilla¹, P Goñi, M C Rubio, J Castillo, L Millán, P Cerdá, J Sahagún, C Pitart, A Beltrán, R Gómez-Lus

Affiliation

¹ Department of Microbiology, Faculty of Medicine, University of Zaragoza, 50009 Zaragoza, Spain.

Abstract

Forty-six Yersinia enterocolitica O:3 clinical isolates resistant to nalidixic acid were studied. The use of molecular typing techniques, other indicators of resistance patterns, the plasmid profile, and the presence of genes that encode aminoglycoside-modifying enzyme production suggested to us a clonal dissemination of the studied strains.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Infective Agents / pharmacology*
Drug Resistance, Bacterial* / genetics
Humans
Microbial Sensitivity Tests
Nalidixic Acid / pharmacology*
Nucleotidyltransferases / genetics
Plasmids / genetics
Yersinia Infections / epidemiology*
Yersinia Infections / microbiology
Yersinia enterocolitica / drug effects*
Yersinia enterocolitica / genetics

Substances

Anti-Infective Agents
Nalidixic Acid
Nucleotidyltransferases
streptomycin 3''-adenylyltransferase