Identification of new okadaic acid derivatives from laboratory cultures of Prorocentrum lima

José J Fernández; Blanca Suárez-Gómez; María L Souto; Manuel Norte

doi:10.1021/np030110u

Identification of new okadaic acid derivatives from laboratory cultures of Prorocentrum lima

J Nat Prod. 2003 Sep;66(9):1294-6. doi: 10.1021/np030110u.

Authors

José J Fernández¹, Blanca Suárez-Gómez, María L Souto, Manuel Norte

Affiliation

¹ Instituto Universitario de Bio-Orgánica Antonio González, Universidad de La Laguna, Astrofísico Francisco Sánchez 2, 38206 La Laguna, Tenerife, Spain.

PMID: 14510622
DOI: 10.1021/np030110u

Abstract

The dinoflagellate Prorocentrum lima produces toxins involved in the red tide phenomenon known as diarrhetic shellfish poisoning (DSP). This paper reports the isolation and spectroscopic structural elucidation of new compounds related to DSP toxins, isolated from a laboratory culture of strain PLV2. Their structures were established from their spectroscopic data.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Chromatography, High Pressure Liquid
Dinoflagellida / chemistry*
Magnetic Resonance Spectroscopy
Marine Toxins / chemistry
Marine Toxins / isolation & purification*
Marine Toxins / pharmacology
Molecular Structure
Okadaic Acid / analogs & derivatives*
Okadaic Acid / chemistry
Okadaic Acid / isolation & purification*
Okadaic Acid / pharmacology
Stereoisomerism
Structure-Activity Relationship

Substances

DTX-6 compound
Marine Toxins
Okadaic Acid