Abstract
The experimental intestinal obstruction model was made by partly ligating the ileum in rat. The histamine levels of obstruction groups (8.14 +/- 2.28 micrograms/g) were obviously lower than those of control groups (P < 0.01). After administration of Dachengqi decoction, Shaogan decoction, emodin and sennoside, the levels of histamine were significantly higher than those of obstruction groups, but there were no significant differences as compared with control groups.
MeSH terms
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Animals
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Anthraquinones / pharmacology
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Cathartics / pharmacology
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Drugs, Chinese Herbal / pharmacology*
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Drugs, Chinese Herbal / therapeutic use
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Emodin / pharmacology
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Female
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Histamine / metabolism*
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Intestinal Mucosa / metabolism*
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Intestinal Obstruction / drug therapy
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Intestinal Obstruction / metabolism*
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Male
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Rats
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Rats, Inbred Strains
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Senna Extract
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Sennosides
Substances
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Anthraquinones
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Cathartics
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Drugs, Chinese Herbal
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Sennosides
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Senna Extract
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Histamine
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Emodin