Abstract
A patient with chronic active hepatitis B was treated with interferon alpha. Inhibition of HBV replication was associated with severe exacerbation of hepatitis. Treatment of chronic hepatitis B with interferon may lead to transient decompensation of liver function, especially in patients with high activity of morphological changes.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Hepatitis B / microbiology
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Hepatitis B / physiopathology
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Hepatitis B / therapy*
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Hepatitis B virus / drug effects
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Hepatitis B virus / physiology
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Hepatitis, Chronic / microbiology
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Hepatitis, Chronic / physiopathology
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Hepatitis, Chronic / therapy*
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Humans
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Interferon-alpha / adverse effects*
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Interferon-alpha / therapeutic use
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Liver / drug effects
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Liver / microbiology
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Liver / physiopathology
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Male
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Middle Aged
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Severity of Illness Index
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Virus Replication / drug effects
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Virus Replication / physiology