[Dissolution of pancreatic calcifications with oral citrates in a woman with chronic idiopathic pancreatitis]

Rev Invest Clin. 1992 Apr-Jun;44(2):249-54.
[Article in Spanish]

Abstract

Pain control is one of the most important objectives in the medical treatment of patients with chronic calcifying pancreatitis (CCP). It is generally accepted that pain in CCP is secondary to the obstruction of the pancreatic duct by calcifications, protein plugs and stenotic areas. Experimental studies have shown that calculi and protein plugs are soluble in citrates. We report here the case of a young non alcoholic woman with idiopathic CCP who after a pancreatojejunostomy developed again pain and pancreatic calcifications which were dissolved with oral citrates. The case confirms previous observations and illustrates the potential use of citrates in subjects with CCP.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Abdominal Pain / etiology
  • Abdominal Pain / physiopathology
  • Abdominal Pain / prevention & control
  • Administration, Oral
  • Adult
  • Calcinosis / complications
  • Calcinosis / drug therapy*
  • Calcinosis / surgery
  • Chronic Disease
  • Citrates / administration & dosage
  • Citrates / therapeutic use*
  • Combined Modality Therapy
  • Female
  • Humans
  • Pancreatic Diseases / complications
  • Pancreatic Diseases / drug therapy
  • Pancreatic Diseases / surgery
  • Pancreatitis / complications
  • Pancreatitis / drug therapy*
  • Pancreatitis / surgery

Substances

  • Citrates