Modulation of rat liver peroxisomal and microsomal fatty acid oxidation by starvation

FEBS Lett. 1992 Sep 28;310(2):193-6. doi: 10.1016/0014-5793(92)81327-i.

Abstract

In this work the microsomal lauric acid omega-hydroxylation, fatty acid peroxisomal beta-oxidation, and the levels of cytochrome P-450 IVA1 were studied in liver tissue from starved rats. Starvation increased the peroxisomal beta-oxidation and the microsomal hydroxylation of fatty acids. The correlation between these activities would support the proposal that both processes are linked, contributing in part to catabolism of fatty acids in liver of starved rats.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blotting, Western
  • Catalase / metabolism
  • Cytochrome P-450 Enzyme System / metabolism
  • Electrophoresis, Polyacrylamide Gel
  • Fatty Acids / metabolism*
  • Hydroxylation
  • Liver / enzymology
  • Liver / metabolism*
  • Male
  • Microbodies / enzymology
  • Microbodies / metabolism*
  • Microsomes, Liver / enzymology
  • Microsomes, Liver / metabolism*
  • Oxidation-Reduction
  • Rats
  • Rats, Wistar
  • Starvation / metabolism*

Substances

  • Fatty Acids
  • Cytochrome P-450 Enzyme System
  • Catalase