Different localization of Epstein-Barr virus genome in two subclones of the Burkitt lymphoma cell line Namalwa

Genes Chromosomes Cancer. 1992 Apr;4(3):205-10. doi: 10.1002/gcc.2870040303.

Abstract

The Epstein-Barr virus genome contained in the Burkitt lymphoma line Namalwa was previously localized to the short arm of chromosome 1. Analysis of a different subline of the same Namalwa line by means of Southern analysis carried out on genomic DNA, as well as in situ hybridization, showed a localization on the X chromosome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blotting, Southern
  • Burkitt Lymphoma / genetics
  • Burkitt Lymphoma / immunology
  • Burkitt Lymphoma / microbiology*
  • Cell Line
  • Chromosomes, Human, Pair 7
  • DNA / analysis
  • HLA Antigens / analysis
  • Herpesvirus 4, Human / genetics*
  • Humans
  • Immunophenotyping
  • Nucleic Acid Hybridization
  • Polymorphism, Restriction Fragment Length
  • Restriction Mapping
  • Trisomy
  • Tumor Cells, Cultured

Substances

  • HLA Antigens
  • DNA