The success of dental implants is primarily dependent upon the degree of osseointegration or bone-to-implant contact (BIC), possibly facilitated by a roughened implant surface. This study was performed to histologically evaluate the nature of osseointegration and bone healing of submerged microtextured implants in eight dogs. Three months following tooth extraction in the posterior mandibulae, three microtextured submerged implants were placed in each quadrant. Block biopsies were harvested at 4 and 16 weeks (four dogs each) following surgery, and histologic preparation was performed. Histomorphometric analysis demonstrated that % BIC value increased marginally from 40% at 4 weeks to 48% at 16 weeks, without a statistically significant difference. The first bone-to-implant contact (f-BIC) at 16 weeks was significantly lower than the 4-week f-BIC (0.81 mm vs. 0.56 mm). In conclusion, this study found minimal change in BIC over time (from 4 to 16 weeks) in unloaded microtextured implants, while the mean f-BIC value significantly increased during this same observation period.