Specific autoantibodies to platelet glycoproteins in Epstein-Barr virus-associated immune thrombocytopenia

Miyuki Tanaka; Takehiko Kamijo; Kenichi Koike; Ichiro Ueno; Yozo Nakazawa; Yumi Kurokawa; Kazuo Sakashita; Atsushi Komiyama; Koji Fujisawa

doi:10.1007/BF02983388

Specific autoantibodies to platelet glycoproteins in Epstein-Barr virus-associated immune thrombocytopenia

Int J Hematol. 2003 Aug;78(2):168-70. doi: 10.1007/BF02983388.

Authors

Miyuki Tanaka¹, Takehiko Kamijo, Kenichi Koike, Ichiro Ueno, Yozo Nakazawa, Yumi Kurokawa, Kazuo Sakashita, Atsushi Komiyama, Koji Fujisawa

Affiliation

¹ Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.

PMID: 12953814
DOI: 10.1007/BF02983388

Abstract

In this study, we detected autoantibodies to platelet glycoproteins GPIIb/IIIa and GPIb/IX on platelets and in plasma in a patient with immune thrombocytopenia associated with Epstein-Barr virus-related infectious mononucleosis. In addition, we present our findings on the effectiveness of intravenous immunoglobulin therapy for immune thrombocytopenia associated with Epstein-Barr virus.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Autoantibodies / blood*
Child, Preschool
DNA, Viral / analysis
Epstein-Barr Virus Infections / immunology*
Herpesvirus 4, Human / genetics
Herpesvirus 4, Human / isolation & purification*
Humans
Male
Platelet Glycoprotein GPIIb-IIIa Complex / immunology
Platelet Glycoprotein GPIb-IX Complex / immunology
Polymerase Chain Reaction
Purpura, Thrombocytopenic, Idiopathic / immunology*
Purpura, Thrombocytopenic, Idiopathic / virology*

Substances

Autoantibodies
DNA, Viral
Platelet Glycoprotein GPIIb-IIIa Complex
Platelet Glycoprotein GPIb-IX Complex