[Quantitative assay of CD8+ (cytotoxic and suppressor) lymphocytes in patients with both asymptomatic and symptomatic HIV infection]

M Radkowski; T Laskus; E Kopicz-Kamińska; L Babiuch; J Slusarczyk

[Quantitative assay of CD8+ (cytotoxic and suppressor) lymphocytes in patients with both asymptomatic and symptomatic HIV infection]

Pol Tyg Lek. 1992 Sep;47(36-37):787-9.

[Article in Polish]

Authors

M Radkowski¹, T Laskus, E Kopicz-Kamińska, L Babiuch, J Slusarczyk

Affiliation

¹ Zakładu Immunopatologii, Kliniki Nabytych Niedoborów Immunologicznych Instytutu Chorób Zakaźnych i Pasozytniczych, Warszawie.

PMID: 1293561

Abstract

Lymphocytes CD8+ have been assayed prospectively in 245 individuals infected with HIV. Percentage and number of CD8+ have been nearly two-fold higher in asymptomatic patients or patients with lymphadenopathy than those in the control group. The number of CD8+ lymphocytes has been rapidly decreasing parallel to the progression of HIV (ARC and AIDS), while their percentage has increased--however insignificantly. There has been a positive correlation between the number of CD4+ and CD8+ cells and all clinical stages of HIV infection.

Publication types

English Abstract

MeSH terms

Adolescent
Adult
CD4-CD8 Ratio
Female
HIV Infections / immunology*
Humans
Leukocyte Count
Male
Middle Aged
Prospective Studies
T-Lymphocytes, Cytotoxic / immunology*
T-Lymphocytes, Regulatory / immunology*