Abstract
Background:
Illicit soft-tissue augmentation performed in New York City resulted in an outbreak of Mycobacterium abscessus infection in 2002.
Objective:
To report two cases of women who developed tender, subcutaneous nodules of the face and buttocks after illicit soft-tissue augmentation with a hyaluronic acid derivative.
Methods:
Two case reports are presented, and the literature is reviewed.
Results:
Empiric treatment with clarithromycin (for M. abscessus infection) and prednisone (for foreign body reaction) resulted in clearance of lesions.
Conclusion:
Contaminated or impure material used for soft-tissue augmentation can result in a clustered outbreak of infection or foreign body reaction.
MeSH terms
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Adult
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Aged
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Anti-Bacterial Agents / therapeutic use
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Clarithromycin / therapeutic use
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Cosmetic Techniques / adverse effects*
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Disease Outbreaks*
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Equipment Contamination*
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Female
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Foreign-Body Reaction / drug therapy
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Foreign-Body Reaction / etiology
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Fraud*
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Glucocorticoids / therapeutic use
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Humans
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Hyaluronic Acid / administration & dosage
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Hyaluronic Acid / adverse effects*
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Hyaluronic Acid / analogs & derivatives
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Injections, Subcutaneous
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Middle Aged
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Mycobacterium Infections, Nontuberculous / drug therapy
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Mycobacterium Infections, Nontuberculous / epidemiology*
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Mycobacterium Infections, Nontuberculous / etiology*
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New York City / epidemiology
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Plastic Surgery Procedures / adverse effects
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Prednisone / therapeutic use
Substances
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Anti-Bacterial Agents
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Glucocorticoids
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Hyaluronic Acid
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Clarithromycin
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Prednisone