Tandem RCM-Pauson-Khand reaction for access to tricycles in one step

Org Biomol Chem. 2003 May 7;1(9):1450-1. doi: 10.1039/b302277c.

Abstract

Starting from conveniently designed dienynes complexed to cobalt, a tandem RCM-intramolecular Pauson-Khand reaction yields tricyclic compounds. The methodology allows the synthesis of 6,5,5 and 7,5,5 systems.