Abstract
We analyzed eight invasive Haemophilus influenzae strains isolated from individual children vaccinated appropriately for their ages. Five of the strains were type b and three were nontypeable strains. Children infected with nontypeable strains had a protective level of anti-H. influenzae type b antibodies, while only one of the children whose cases represented true vaccine failure did.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Child, Preschool
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HIV Infections / complications
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Haemophilus Infections / epidemiology*
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Haemophilus Infections / immunology
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Haemophilus Infections / prevention & control*
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Haemophilus Vaccines / therapeutic use*
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Haemophilus influenzae type b / classification
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Haemophilus influenzae type b / genetics*
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Humans
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Infant
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Molecular Epidemiology
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Phylogeny
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Risk Factors
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Treatment Failure
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Vaccines, Conjugate / therapeutic use*
Substances
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Haemophilus Vaccines
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Vaccines, Conjugate