Drug rash with eosinophilia and systemic symptoms secondary to phenobarbitone

Clin Neuropharmacol. 2003 Jul-Aug;26(4):177-8. doi: 10.1097/00002826-200307000-00004.

Abstract

The authors describe a case of a rare, potentially fatal multisystem reaction, recently called drug rash with eosinophilia and systemic symptoms (or DRESS) resulting from phenobarbitone. They highlight the main characteristics of this syndrome and the diagnostic difficulties.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Eosinophilia / chemically induced*
  • Eosinophilia / complications
  • Eosinophilia / diagnosis
  • Exanthema / chemically induced*
  • Exanthema / complications
  • Exanthema / diagnosis
  • Female
  • Humans
  • Multiple Organ Failure / chemically induced*
  • Multiple Organ Failure / complications
  • Multiple Organ Failure / diagnosis
  • Phenobarbital / adverse effects*

Substances

  • Phenobarbital