Synthesis of mannose-containing analogues of (1-->6)-branched (1-->3)-glucohexaose (I)

Carbohydr Res. 2003 Aug 12;338(17):1727-35. doi: 10.1016/s0008-6215(03)00263-5.

Abstract

alpha-D-Manp-(1-->3)-[alpha-D-Manp-(1-->6)]-alpha-D-Glcp-(1-->3)-beta-D-Glcp-(1-->3)-[alpha-D-Manp-(1-->6)]-D-Glcp and alpha-D-Manp-(1-->3)-[beta-D-Glcp-(1-->6)]-alpha-D-Glcp-(1-->3)-beta-D-Glcp-(1-->3)[-alpha-D-Manp-(1-->6)]-D-Glcp were synthesized in a regio- and stereoselective way as the mannose-containing analogues of the immunomodulating beta-D-Glcp-(1-->3)-[beta-D-Glcp-(1-->6)]-alpha-D-Glcp-(1-->3)-beta-D-Glcp-(1-->3)-[beta-D-Glcp-(1-->6)]-D-Glcp.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbohydrate Conformation
  • Carbohydrate Sequence
  • Glucose / analogs & derivatives*
  • Glycosylation
  • Mannose / analogs & derivatives*
  • Molecular Sequence Data
  • Oligosaccharides / chemical synthesis*
  • Stereoisomerism

Substances

  • Oligosaccharides
  • Glucose
  • Mannose