[Usefulness of 3D-VIBE method in breast dynamic MRI: imaging parameters and contrasting effects]

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2003 Jun;59(6):759-64. doi: 10.6009/jjrt.kj00003174159.
[Article in Japanese]

Abstract

MR imaging (MRI) has been reported to be a useful modality to characterize breast tumors and to evaluate disease extent. Contrast-enhanced dynamic MRI, in particular, allows breast lesions to be characterized with high sensitivity and specificity. Our study was designed to develop three-dimensional volumetric interpolated breath-hold examination (3D-VIBE) techniques for the evaluation of breast tumors. First, agarose/Gd-DTPA phantoms with various concentrations of Gd-DTPA were imaged using 3D-VIBE and turbo spin echo (TSE). Second, one of the phantoms was imaged with 3D-VIBE using different flip angles. Finally, water excitation (WE) and a chemical shift-selective (CHESS) pulse were applied to the images. Each image was analyzed for signal intensity, signal-to-noise ratio (1.25*Ms/Mb) (SNR), and contrast ratio [(Ms1-Ms2)/[(Ms1+Ms2)/2]]. The results showed that 3D-VIBE provided better contrast ratios with a linear fit than TSE, although 3D-VIBE showed a lower SNR. To reach the best contrast ratio, the optimized flip angle was found to be 30 degrees for contrast-enhanced dynamic study. Both WE and CHESS pulses were reliable for obtaining fat-suppressed images. In conclusion, the 3D-VIBE technique can image the entire breast area with high resolution and provide better contrast than TSE. Our phantom study suggests that optimized 3D-VIBE may be useful for the assessment of breast tumors.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Breast Neoplasms / diagnosis*
  • Contrast Media
  • Female
  • Gadolinium DTPA
  • Humans
  • Imaging, Three-Dimensional / methods
  • Magnetic Resonance Imaging / methods*
  • Phantoms, Imaging
  • Sensitivity and Specificity

Substances

  • Contrast Media
  • Gadolinium DTPA