[A familial form of medullary carcinoma of the thyroid gland]

D L Rotin; V Zh Brzhezovskiĭ; A I Pavlovskaia; E A Smirnova; O A Anurova

[A familial form of medullary carcinoma of the thyroid gland]

Arkh Patol. 2003 May-Jun;65(3):7-9.

[Article in Russian]

Authors

D L Rotin¹, V Zh Brzhezovskiĭ, A I Pavlovskaia, E A Smirnova, O A Anurova

Affiliation

¹ N. N. Blokhin Cancer Research Center, 115478, Moscow.

PMID: 12879602

Abstract

A case of a family form of medullary thyroid cancer is reported. Histological, immunohistochemical and ultrastructural data are presented and problems of etiology, pathogenesis and diagnosis are discussed.

Publication types

Case Reports
English Abstract

MeSH terms

Adult
Calcitonin / biosynthesis
Carcinoma, Medullary / genetics*
Carcinoma, Medullary / ultrastructure
Female
Genetic Predisposition to Disease
Humans
Immunohistochemistry
Microscopy, Electron
Mutation
Oncogene Proteins / genetics*
Proto-Oncogene Proteins c-ret
Receptor Protein-Tyrosine Kinases / genetics*
Thyroid Neoplasms / genetics*
Thyroid Neoplasms / ultrastructure
Thyroidectomy

Substances

Oncogene Proteins
Calcitonin
Proto-Oncogene Proteins c-ret
RET protein, human
Receptor Protein-Tyrosine Kinases