Infection with human herpesvirus-8 and its correlation with hepatitis B virus and hepatitis C virus markers among rural populations in Cambodia

Am J Trop Med Hyg. 2003 Apr;68(4):501-2.

Abstract

Among 164 individuals in a rural population of Cambodia, antibodies to human herpesvirus-8 (HHV-8) were found among 56.6% of the women and 50.6% of the men. Seropositivity for HHV-8 tended to decrease with age (P < 0.001) and was not associated with exposure to hepatitis B virus (HBV) or HCV. Human herpesvirus-8, which shows a high rate of infection during childhood, does not seem to have the same pattern of transmission as HBV. This suggests very early acquisition of infection with HHV-8 in Cambodia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Antibodies, Viral / blood
  • Cambodia / epidemiology
  • Child
  • Child, Preschool
  • Confidence Intervals
  • Female
  • Hepatitis B / complications
  • Hepatitis B / epidemiology*
  • Hepatitis B Surface Antigens / blood
  • Hepatitis C / complications
  • Hepatitis C / epidemiology*
  • Hepatitis C Antibodies / blood
  • Herpesvirus 8, Human / immunology*
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Odds Ratio
  • Rural Population*
  • Sarcoma, Kaposi / complications
  • Sarcoma, Kaposi / epidemiology*
  • Seroepidemiologic Studies

Substances

  • Antibodies, Viral
  • Hepatitis B Surface Antigens
  • Hepatitis C Antibodies