Building antibodies from their genes

Immunol Rev. 1992 Dec:130:41-68. doi: 10.1111/j.1600-065x.1992.tb01520.x.

Authors

H R Hoogenboom¹, J D Marks, A D Griffiths, G Winter

Affiliation

¹ MRC Centre for Protein Engineering, Cambridge, UK.

PMID: 1286871
DOI: 10.1111/j.1600-065x.1992.tb01520.x

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Antibodies / genetics*
Antibody Affinity
B-Lymphocytes / immunology
Bacteriophages / genetics
Binding Sites, Antibody
Capsid / genetics
Gene Rearrangement, B-Lymphocyte
Genes, Immunoglobulin*
Hybridomas / immunology
Immunoglobulin Variable Region / genetics*
Mice
Plasma Cells / immunology
Polymerase Chain Reaction
Protein Engineering*
Recombinant Fusion Proteins / biosynthesis
Recombinant Fusion Proteins / genetics*
Selection, Genetic

Substances

Antibodies
Immunoglobulin Variable Region
Recombinant Fusion Proteins