Abstract
An extract of the leaves of Morierina montana collected in New Caledonia was found to be cytotoxic for KB cells. A bioassay-guided fractionation procedure led to the isolation of a series of cucurbitacins of which one, morierinin (1), is new. The isolation and structure elucidation of 1 are described.
MeSH terms
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Plant Extracts / chemistry
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Plant Extracts / isolation & purification
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Plant Leaves / chemistry*
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Rubiaceae / chemistry*
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Triterpenes / chemistry*
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Triterpenes / isolation & purification*
Substances
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Plant Extracts
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Triterpenes
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morierinin
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cucurbitacin B
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cucurbitacin E
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23,24-dihydrocucurbitacin B