Introduction: Turner syndrome (TS) is a chromosomal disorder occurring in approximately 1/2000 living female births and its essence is existence of only one normal X chromosome. There are data from many centres interested in TS which confirm increased frequency of impaired glucose tolerance, insulin resistance and diabetes mellitus (DM) type 2 in TS. Knowledge about DM type 1 in this syndrome is very limited.
Aim of study: There are 2 girls in our clinic with TS (from among 75 diagnosed and treated) in whom diabetes mellitus was diagnosed and required insulinotherapy (type 1).
The aim of the work: presentation of clinical appearance of TS and DM type 1 in both girls.
A case report: Patient LA: not very characteristic fenotype, karyotype 45,X, TS recognised in the age of 10-years, DM - 11-years. Patient BE: characteristic features, karyotype 45,X, TS recognised in the age of 8-years, DM - 3-years.
Conclusion: 1. Each Turner syndrome case ought to arouse "diabetic vigilance". 2. Observation toward Turner syndrome is advisable in each short patient with diabetes mellitus.