The high-resolution solution structure of epothilone A bound to tubulin: an understanding of the structure-activity relationships for a powerful class of antitumor agents

Angew Chem Int Ed Engl. 2003 Jun 6;42(22):2511-5. doi: 10.1002/anie.200351276.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antineoplastic Agents / chemistry*
  • Cattle
  • Epothilones / chemistry*
  • Models, Molecular
  • Molecular Conformation
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular*
  • Solutions / chemistry
  • Structure-Activity Relationship
  • Tubulin / chemistry*

Substances

  • Antineoplastic Agents
  • Epothilones
  • Solutions
  • Tubulin
  • epothilone A