First-trimester diagnosis of nuchal anomalies: significance and fetal outcome

Y Ville; C Lalondrelle; S Doumerc; F Daffos; R Frydman; J F Oury; Y Dumez

doi:10.1046/j.1469-0705.1992.02050314.x

First-trimester diagnosis of nuchal anomalies: significance and fetal outcome

Ultrasound Obstet Gynecol. 1992 Sep 1;2(5):314-6. doi: 10.1046/j.1469-0705.1992.02050314.x.

Authors

Y Ville¹, C Lalondrelle, S Doumerc, F Daffos, R Frydman, J F Oury, Y Dumez

Affiliation

¹ Clinique Universitaire Port-Royal, Hopital Cochin, Paris, France.

PMID: 12796927
DOI: 10.1046/j.1469-0705.1992.02050314.x

Abstract

High-resolution real-time ultrasonography now permits the differentiation between nuchal translucencies and cystic hygromata of the neck in the first trimester. A series of 85 nuchal anomalies are presented that were diagnosed by ultrasonography at 9-14 weeks' gestation; their association with chromosomal defects and fetal outcome are also presented. Chromosomal anomalies were found in 8/29 nuchal translucencies and in 16/56 cystic hygromata of the neck. However, in fetuses with normal karyotype, additional defects were diagnosed in l0/40 fetuses with cystic hygromata and in none with nuchal translucency. These data may be important for the management of these conditions and for counselling the patients toward further pregnancy.