Abstract
We evaluated the ability of epitope-blocking enzyme-linked immunosorbent assays (ELISAs) to detect West Nile virus (WNV) antibodies in domestic mammals. Sera were collected from experimentally infected horses, cats, and pigs at regular intervals and screened in ELISAs and plaque reduction neutralization tests. The diagnostic efficacies of these techniques were similar.
Publication types
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Evaluation Study
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Animals, Domestic* / virology*
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Antibodies, Monoclonal / immunology
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Antibodies, Viral / blood*
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Cat Diseases / virology
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Cats
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Enzyme-Linked Immunosorbent Assay / methods
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Epitopes / immunology
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Horse Diseases / virology
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Horses
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Neutralization Tests
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Swine
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Swine Diseases / virology
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Viral Plaque Assay
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West Nile Fever / diagnosis
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West Nile Fever / veterinary*
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West Nile virus / immunology*
Substances
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Antibodies, Monoclonal
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Antibodies, Viral
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Epitopes