First total synthesis of the neuronal cell protecting carbazole alkaloid carbazomadurin A by sequential transition metal-catalyzed reactions

Chem Commun (Camb). 2003 May 21:(10):1170-1. doi: 10.1039/b301979a.

Abstract

The highly oxygenated neuronal cell protecting carbazole alkaloid carbazomadurin A was synthesized in nine steps and 11% overall yield from isovanillic acid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaloids / chemical synthesis*
  • Alkaloids / chemistry
  • Carbazoles / chemical synthesis*
  • Carbazoles / chemistry
  • Catalysis
  • Cytoprotection*
  • Metals / chemistry*
  • Molecular Structure
  • Neurons / cytology*

Substances

  • Alkaloids
  • Carbazoles
  • Metals
  • carbazomadurin A