Assessment of anticolitic drugs in the trinitrobenzene sulfonic acid (TNBS) rat model of inflammatory bowel disease

Methods Mol Biol. 2003:225:209-22. doi: 10.1385/1-59259-374-7:209.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Administration, Oral
  • Animals
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / therapeutic use*
  • Arginine / metabolism
  • Blotting, Western
  • Colitis / chemically induced
  • Colitis / drug therapy*
  • Colitis / pathology
  • Disease Models, Animal*
  • Drug Evaluation, Preclinical / methods*
  • Enzyme Inhibitors / pharmacology
  • Inflammatory Bowel Diseases*
  • Injections, Subcutaneous
  • Instillation, Drug
  • Male
  • Models, Animal*
  • NG-Nitroarginine Methyl Ester / pharmacology
  • Neutrophils / enzymology
  • Nitric Oxide Synthase / antagonists & inhibitors
  • Nitric Oxide Synthase / metabolism
  • Nitric Oxide Synthase Type II
  • Peroxidase / analysis
  • Rats
  • Rats, Wistar
  • Trinitrobenzenesulfonic Acid / toxicity*

Substances

  • Anti-Inflammatory Agents
  • Enzyme Inhibitors
  • Trinitrobenzenesulfonic Acid
  • Arginine
  • Peroxidase
  • Nitric Oxide Synthase
  • Nitric Oxide Synthase Type II
  • Nos2 protein, rat
  • NG-Nitroarginine Methyl Ester