Evaluation of complications and results in a contemporary series of 300 consecutive radical retropubic prostatectomies with the anatomic approach at a single institution

Urology. 2003 May;61(5):982-6. doi: 10.1016/s0090-4295(02)02517-7.

Abstract

Objectives: To evaluate the complications and results of radical retropubic prostatectomy with the anatomic approach, at our center, to allow a comparison with published studies and precise patient counseling.

Methods: We reviewed the charts and records of the follow-up visits of all patients who consecutively underwent radical retropubic prostatectomy for clinically intracapsular prostate cancer between March 1997 and February 2002.

Results: The pathologic stage was pT0 in 4 patients (1.3%), pT2a in 83 (27.7%), pT2b in 116 (38.7%), pT3a in 52 (17.3%), pT3b in 38 (12.6%), and pT4 in the remaining 7 (2.4%). Extracapsular disease extension was present in 97 specimens (32.3%); it was associated with positive margins in 64 patients (21.3%). Intraoperative and postoperative complications were recorded in 19 patients (6.3%). Immediate surgical repair was necessary in 3 cases (1%) and delayed in 5 (1.7%). A stricture of the vesicourethral anastomosis was observed in 2 patients (0.7%). At a median follow-up of 29 months (range 6 to 57), a total of 262 patients (88.8%) was continent; 26 patients (8.8%) had stress incontinence, and 7 were incontinent (2.3%). Of 262 patients, 128 (48.2%) achieved continence within the first day of catheter removal.

Conclusions: Radical retropubic prostatectomy is associated with low complication rates; with the anatomic approach, a limited incidence of incontinence is attainable, consistent with major referral centers.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Anastomosis, Surgical / adverse effects
  • Anastomosis, Surgical / methods
  • Constriction, Pathologic / epidemiology
  • Constriction, Pathologic / surgery
  • Counseling / methods
  • Erectile Dysfunction / epidemiology
  • Follow-Up Studies
  • Humans
  • Incidence
  • Intraoperative Complications / epidemiology*
  • Intraoperative Complications / surgery
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Postoperative Care / methods
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / surgery
  • Prostate-Specific Antigen / blood
  • Prostatectomy / adverse effects*
  • Prostatectomy / methods*
  • Prostatic Neoplasms / blood
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / surgery*
  • Urethra / surgery
  • Urinary Bladder / surgery
  • Urinary Incontinence / epidemiology
  • Urinary Incontinence, Stress / epidemiology

Substances

  • Prostate-Specific Antigen