Synthesis of fluorinated 1-(3-morpholin-4-yl-phenyl)-ethylamines

Bioorg Med Chem Lett. 2003 May 19;13(10):1725-8. doi: 10.1016/s0960-894x(03)00240-3.

Abstract

The synthesis of four (+/-)-fluorinated 1-(3-morpholin-4-yl-phenyl)-ethylamines and an enantioselective approach to these amines through reductive amination are described.

MeSH terms

  • Anti-Bacterial Agents / chemical synthesis*
  • Fluorine / chemistry
  • Molecular Structure
  • Morpholines / chemistry
  • Phenethylamines / chemical synthesis*
  • Stereoisomerism

Substances

  • Anti-Bacterial Agents
  • Morpholines
  • Phenethylamines
  • Fluorine