Dispatch. Cell division: the place and time of cytokinesis

Curr Biol. 2003 Apr 29;13(9):R363-5. doi: 10.1016/s0960-9822(03)00278-1.

Abstract

Recent studies have provided evidence that, during cytokinesis, activation of the Pbl-Rho1 pathway by a protein complex located at the spindle midzone, and inhibition of this pathway by two mitotic cyclins, may be major contributing factors controlling the place and timing of the cleavage furrow.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Division / physiology*
  • Cyclins / physiology
  • Drosophila Proteins / physiology*
  • Gene Expression Regulation / physiology*
  • Guanine Nucleotide Exchange Factors / physiology*
  • Models, Biological
  • Spindle Apparatus / physiology

Substances

  • Cyclins
  • Drosophila Proteins
  • Guanine Nucleotide Exchange Factors
  • Pbl protein, Drosophila