Dendritic cells, new tools for vaccination

Microbes Infect. 2003 Apr;5(4):311-9. doi: 10.1016/s1286-4579(03)00033-9.

Abstract

Our rapidly expanding knowledge of the biology of the dendritic cell (DC), a major antigen-presenting cell connecting innate and adaptive immunity, suggests new possibilities for the development of vaccines and therapeutic strategies against pathogens, through the manipulation of their function in vivo, or the injection of the DC itself, once properly instructed ex vivo.

Publication types

  • Review

MeSH terms

  • Adjuvants, Immunologic / therapeutic use
  • Antigen-Presenting Cells / immunology
  • Dendritic Cells / drug effects
  • Dendritic Cells / immunology*
  • Dendritic Cells / transplantation
  • Humans
  • Immunotherapy / methods
  • Infections / therapy*
  • Lipopolysaccharides / immunology
  • Lipopolysaccharides / therapeutic use
  • Models, Biological
  • Vaccination / methods
  • Vaccines* / administration & dosage

Substances

  • Adjuvants, Immunologic
  • Lipopolysaccharides
  • Vaccines