A coupled numerical model of the atmospheric thermo-hydrodynamics and pollutant photochemical transport is described. This model can be used to study the complex relationships between the chemical and thermo-hydrodynamic processes in the atmosphere of urban areas with an emphasis on photochemical ozone formation. Preliminary numerical results of ozone and other key chemical atmospheric pollutant concentrations and distribution across the Houston-Galveston-Brazoria area using virtual emission data from area and mobile sources are presented.