Apoptosis in peripheral blood leukocytes induced by hyperthermia and prednisolone in patients with dysadaptation

Bull Exp Biol Med. 2002 Dec;134(6):531-3. doi: 10.1023/a:1022992524357.

Abstract

We studied morphological changes in blood leukocytes produced by prednisolone and hyperthermia. Patients with dysadaptation were characterized by activation of spontaneous apoptosis and inhibition of induced apoptosis in neutrophils and lymphocytes compared to healthy donors.

Publication types

  • Comparative Study

MeSH terms

  • Adaptation, Physiological*
  • Adult
  • Anti-Inflammatory Agents / pharmacology*
  • Apoptosis / drug effects*
  • Apoptosis / physiology*
  • Female
  • Fever*
  • Humans
  • Leukocytes / drug effects*
  • Male
  • Neutrophils / drug effects
  • Prednisolone / pharmacology*

Substances

  • Anti-Inflammatory Agents
  • Prednisolone