Early cord clamping protects at-risk neonates from polycythemia

Biol Neonate. 2003;83(3):197-200. doi: 10.1159/000068933.

Abstract

Neonatal polycythemia is a potentially lethal, multi-organ disease. We have performed a prospective, open-label study to test the hypothesis that an early cord clamping proximally to the neonate's abdomen could avert from the neonatal circulation a blood volume critical to the occurrence of polycythemia in at-risk neonates. Newborns were divided into group 1 (clamping time within 10 s) and group 2 (clamping time 11-120 s). Group 1 had statistically significant more blood volume sequestered in the cord and less manifestations of polycythemia.

Conclusion: An early cord clamping is an effective and zero-cost way to prevent polycythemia in at-risk neonates.

MeSH terms

  • Blood Volume
  • Constriction*
  • Humans
  • Infant, Newborn
  • Polycythemia / prevention & control*
  • Prospective Studies
  • Time Factors
  • Umbilical Cord* / blood supply