Photoinactivation of bacterial strains involved in periodontal diseases sensitized by porphycene-polylysine conjugates

Federico M Lauro; Patrizia Pretto; Loredana Covolo; Giulio Jori; Giulio Bertoloni

doi:10.1039/b200977c

Photoinactivation of bacterial strains involved in periodontal diseases sensitized by porphycene-polylysine conjugates

Photochem Photobiol Sci. 2002 Jul;1(7):468-70. doi: 10.1039/b200977c.

Authors

Federico M Lauro¹, Patrizia Pretto, Loredana Covolo, Giulio Jori, Giulio Bertoloni

Affiliation

¹ Department of Histology, Microbiology and Medical Biotechnology, University of Padova, Via A. Gabelli 63, 35121 Padova, Italy.

PMID: 12659156
DOI: 10.1039/b200977c

Abstract

Selected bacterial strains that are responsible for periodontal diseases are efficiently inactivated by visible light irradiation in the presence of porphycene-polylysine conjugates. Repeated photosensitization of surviving cells does not induce the selection of resistant bacterial strains and does not modify their sensitivity to antibiotic treatment.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacteria / drug effects*
Bacteria / pathogenicity
Bacteria / radiation effects
Humans
Light*
Periodontal Diseases / microbiology*
Photosensitizing Agents / pharmacology*

Substances

Photosensitizing Agents