Orthokeratology lens-related Pseudomonas aeruginosa infectious keratitis

Cornea. 2003 Apr;22(3):265-6. doi: 10.1097/00003226-200304000-00018.

Abstract

Purpose: To report a case of orthokeratology lens-related Pseudomonas corneal ulcer in an adult.

Methods: Case report.

Results: A 37-year-old man presented with a 1-day history of painful red eye. He was a soft contact lens wearer before he started on nocturnal orthokeratology lens wear of 8 to 10 hours per night 9 months ago. Corneal scraping sent for culture revealed a heavy growth of Pseudomonas aeruginosa. The patient was treated with intensive topical fortified tobramycin and ceftazidime drops. The ulcer healed with a residual paraxial corneal scar. Although his best-corrected visual acuity (BCVA) recovered from finger counting (8/200) at presentation to 20/30, he suffered visual loss from a premorbid BSCVA of 20/15. His contrast sensitivity (Vector Vision CSV 1000 test) performance was also worse than his fellow eye.

Conclusion: Nocturnal orthokeratology lens wear may be associated with an increased risk of infection.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Ceftazidime / therapeutic use
  • Contact Lenses / adverse effects*
  • Cornea / microbiology
  • Corneal Ulcer / diagnosis
  • Corneal Ulcer / drug therapy
  • Corneal Ulcer / microbiology*
  • Drug Therapy, Combination / therapeutic use
  • Eye Infections, Bacterial / diagnosis
  • Eye Infections, Bacterial / drug therapy
  • Eye Infections, Bacterial / etiology*
  • Humans
  • Male
  • Myopia / therapy
  • Pseudomonas Infections / diagnosis
  • Pseudomonas Infections / drug therapy
  • Pseudomonas Infections / etiology*
  • Pseudomonas aeruginosa / isolation & purification
  • Tobramycin / therapeutic use
  • Visual Acuity

Substances

  • Anti-Bacterial Agents
  • Ceftazidime
  • Tobramycin