Evaluation of antidiabetic effect of Momordica cymbalaria fruit in alloxan-diabetic rats

Fitoterapia. 2003 Feb;74(1-2):7-13. doi: 10.1016/s0367-326x(02)00297-6.

Abstract

The oral treatment with the aqueous extract of Momordica cymbalaria fruit (MC) (0.5 g/kg) for 6 weeks showed a significant antihyperglycemic as well as antihyperlipidemic effects in the alloxan-induced diabetic rats.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alloxan
  • Animals
  • Blood Glucose / drug effects
  • Blood Glucose / metabolism
  • Cholesterol / blood
  • Cholesterol, HDL / blood
  • Cholesterol, HDL / drug effects
  • Cholesterol, LDL / blood
  • Cholesterol, LDL / drug effects
  • Diabetes Mellitus, Experimental / chemically induced
  • Diabetes Mellitus, Experimental / drug therapy
  • Fruit
  • Hyperlipidemias / chemically induced
  • Hyperlipidemias / drug therapy
  • Hypoglycemic Agents / administration & dosage
  • Hypoglycemic Agents / pharmacology*
  • Hypoglycemic Agents / therapeutic use
  • Hypolipidemic Agents / administration & dosage
  • Hypolipidemic Agents / pharmacology*
  • Hypolipidemic Agents / therapeutic use
  • Insulin / blood
  • Male
  • Momordica*
  • Phytotherapy*
  • Plant Extracts / administration & dosage
  • Plant Extracts / pharmacology*
  • Plant Extracts / therapeutic use
  • Rats
  • Rats, Wistar
  • Triglycerides / blood

Substances

  • Blood Glucose
  • Cholesterol, HDL
  • Cholesterol, LDL
  • Hypoglycemic Agents
  • Hypolipidemic Agents
  • Insulin
  • Plant Extracts
  • Triglycerides
  • Alloxan
  • Cholesterol