To find out the distribution pattern of hair fluoride and its affected factors in coal-exposed environment, human hairs were collected according epidemiological investigation, and contents of fluoride and other life-relative elements in the samples were determined. Results shown that the fluoride content in human hairs had a notable individual differentia, its distribution pattern was anomalous distribution with average fluoride content 67.08 +/- 64.68 micrograms/g and coefficient of variation 96.42%. There were significant positive correlation between F and Ca, Mn, Se as well as significant negative correlation between F and Ti. Factor analysis shown the fluoride content in human hairs was affected by factors such as inner biochemical reaction, outer geochemical environment, structure of food-web and quality of drinking water.